Semaglutide or Ozempic: Which Weight Management Solution is Better?

Obesity is a condition that has led to further chronic and life-threatening complications in some of its patients. Examples of these conditions include hypertension, insulin resistance, hyperlipidemia, among others. Before discovering semaglutide, obese people relied on lifestyle intervention methods to cut down on their weight.
Obesity is a condition that has led to further chronic and life-threatening complications in some of its patients. Examples of these conditions include hypertension, insulin resistance, hyperlipidemia, among others. Before discovering semaglutide, obese people relied on lifestyle intervention methods to cut down on their weight.

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However, with semaglutide, obese patients finally have a more effective way of cutting down on their weight.

However, with semaglutide, obese patients finally have a more effective way of cutting down on their weight.

Semaglutide

Semaglutide is a drug in the category of medicines known as glucagon-like peptide-1 (GLP1) agonists or incretin mimetics. These drugs mimic the action of leptin (the satiety hormone) in the body. They also act by increasing insulin secretion, hence increasing the rate of sugar metabolism. The drug has been proved to help obese or overweight people to cut down on their baseline weight. The drug successfully passed through a clinical trial that compared people using the drug to those on a placebo.

Semaglutide Forms

The drug is marketed in two forms presently: the tablet and subcutaneous injections forms. It is mostly used in combination with a diet and exercise program by people with type-2 diabetes. Despite its beneficial effect, the drug could have serious gastrointestinal side effects such as constipation, vomiting, nausea. Also, the drug shouldn’t be used with any sugar-lowering drug such as sulphonylurea. This could lead to hypoglycemia which could cause dizziness, anxiety, headaches, hunger, and other side effects.

For administration of the tablet, it should be taken 30 to 60 minutes before food for maximum effects.

Ozempic

Ozempic, on the other hand, is just a subcutaneous injection brand of semaglutide. This means there’s actually NO difference between semaglutide and Ozempic. However, the drug is not advertised by its manufacturers as a weight-loss drug. Instead, it is made for those with type-2 diabetes to help with their sugar problems. It is also meant for reducing the risk of major cardiovascular events such as heart attack, stroke, or death in adults with type 2 diabetes with known heart diseases.

The injection is prescribed to be self-administered once weekly. In most cases, the drug should be started at a lower dose before the doctor increases the dose, depending on how the patient’s body reacts to the drug. It is also advised that the injection is taken on the same day of the week.

For Whom It May Apply?

Patients with a personal or family history of medullary thyroid carcinoma (MTC), a type of thyroid cancer, or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) are advised not to use Ozempic. Also, patients with a history of diabetic retinopathy, kidney or pancreas problems are advised to stay from Ozempic. Also, it is NOT meant for use in patients with type 1 diabetes.

Semaglutide or Ozempic?

Finally, it should be noted that there is NO significant difference between semaglutide and Ozempic. Ozempic is just a subcutaneous injection brand of semaglutide. However, if compared to the tablet form of semaglutide, it might elicit its effects faster since it can enter the systemic circulation faster. However, both contain the constituent, elicit their effects using the same mechanism, and have the same side effects, hence, having the same safety levels.

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