A recent study reported the discovery of a crucial portion of the immune system that offers vital information to create vaccines for illnesses such as Malaria and COVID-19.
The study highlighted that an individual’s immune system consists of various cell types, including white blood cells and others.
The team evaluated some white blood cells
The study authors focused on a few white blood cells such as B and T cells and CD4+, among others. The researchers, who were from the University of Tokyo, illustrated that following an attack from an infection, the T cells transmit a message to the B cells.
The B cells, in turn, study and recall the pathogens that it is required to attack. Furthermore, transmission between the two cells is done in one of the organs present in the immune system.
One of the leading study authors and a professor from the University of Tokyo, Michelle S.J. Lee, stated that the development of a vaccine is associated with various factors. The authors should not only focus on the cells in charge of transmitting the immune system as a whole.
The study authors experimented with genetically altered mice with the TBK1 gene present in specific cells. In addition, the mice that do not possess the gene are at a higher rate of dying from infections such as Malaria, among others.
The TBK-1 is a gene that is an enzyme that changes the features of cells and proteins that increase the level of chemical tags via a process known as phosphorylation. Researchers reported that the microscopic images of the cells of the genetically modified rodents indicated that the germinal framework was in specific cells.
The gene enabled researchers to find the types of genes operating in different body cells
The TBK-1 gave the study authors an indication of what other types of genes can run in various body cells. They also reported that the decline of the TBK-1 had no visible effect on the framework on how the rodents faired with the injected infections such as Malaria.
The researchers anticipate that the study’s outcome will provide sufficient information on revealing the mysterious works of the immune system.
